The files in this data release are those referenced in the journal article by Neely and others (2026) entitled "Assessment of antibiotic resistance genes in Caribbean corals, including those treated with amoxicillin." They represent the raw fluorescence data and threshold cycle (Ct) data generated from quantitative polymerase chain reaction (qPCR) microarray runs using deoxyribonucleic acid (DNA) extractions from 12 coral (Colpophyllia natans) samples as templates. These files were produced by the Applied ...